CASE STUDIES | ACHIEVEMENTS
事例・実績
動脈硬化症の早期発見技術開発
Development of a novel technique for early detection of arteriosclerosis
概要_Abstract
動脈硬化性疾患を未然に発見できるような新しい動脈硬化度計測技術を研究開発しています(^_^)
We are challenging to develop a novel technique for early detection of arteriosclerosis.
発表論文_Articles
Yamakoshi T, Rolfe P, Yamakoshi K (2025) Smartphone-based assessment of vasomotor function via fingertip arteriolar elasticity using the volume-oscillometric method with green-light photoplethysmography. Ann Biomed Eng under review. doi:TBA
Yamakoshi K, Rolfe P, Yamakoshi T (2025) Arteriolar elasticity measurement in the fingertip based on photoplethysmographic volume-oscillometry: a new approach to the assessment of vasomotor functions in the microvasculature. Cardiovasc Eng Technol 16: 272-278. doi:10.1007/s13239-025-00772-3
Yamakoshi T, Rolfe P, Yamakoshi K (2022) Peripheral arterial elasticity changes derived by volume-oscillometry in reaction to hyperemia as a possible assessment of flow-mediated vasodilatation. Sci Rep 12 (1):19479. doi:10.1038/s41598-022-22050-1
Yamakoshi T, Rolfe P, Kamiya A, Yamakoshi K (2021) Volume elastic modulus with exponential function of transmural pressure as a valid stiffness measure derived by photoplethysmographic volume-oscillometry in human finger and radial arteries: potential for arteriosclerosis screening. Med Biol Eng Comput 59 (7-8):1585-1596. doi:10.1007/s11517-021-02391-1
Yamakoshi T, Matsumura K, Rolfe P, Hanaki S, Ikarashi A, Lee J, Yamakoshi K (2014) Potential for health screening using long-term cardiovascular parameters measured by finger volume-oscillometry: pilot comparative evaluation in regular and sleep-deprived activities. IEEE J Biomed Health Inform 18 (1):28-35. doi:10.1109/JBHI.2013.2274460
Shimazu H, Yamakoshi K, Kamiya A (1986) Noninvasive measurement of the volume elastic modulus in finger arteries using photoelectric plethysmography. IEEE Trans Biomed Eng 33 (8):795-798. doi:10.1109/TBME.1986.325906
Yamakoshi K, Shimazu H, Shibata M, Kamiya A (1982) New oscillometric method for indirect measurement of systolic and mean arterial pressure in the human finger. Part 2: correlation study. Med Biol Eng Comput 20 (3):314-318. doi:10.1007/BF02442798
深部体温の計測技術開発
Development of a novel technique for measuring body core temperature
概要_Abstract
熱中症予防や基礎体温管理のための新しい深部体温計測技術を研究開発しています(^_^)
We are challenging to develop a novel technique for measuring body core temperature, preventing heat stroke, managing basal body temperature and so on.
発表論文_Articles
Yamakoshi T, Rolfe P, Yamakoshi K (2024) A new noninvasive technique for heat-flux-based deep body thermometry together with possible estimation of thermal resistance of the skin tissue. Med Biol Eng Comput 62 (4):1229-1246. doi:10.1007/s11517-023-02991-z
Yamakoshi T, Matsumura K, Rolfe P, Tanaka N, Yamakoshi Y, Takahashi K (2013) A novel method to detect heat illness under severe conditions by monitoring tympanic temperature. Aviat Space Environ Med 84 (7):692-700. doi:10.3357/ASEM.3542.2013
山越健弘, 田中直登, 山越康弘, 松村健太, Rolfe P, 廣瀬元, 高橋規一 (2010) イヤホン組込型深部体温連続計測装置の開発と安全支援を目指したGTドライバーへの応用. 生体医工学 48 (5):494-504. doi:10.11239/jsmbe.50.227
山越健弘, 松村健太, 山越康弘, 廣瀬元, 高橋規一, Rolfe P (2010) 高温熱ストレス環境下におけるレーシングドライバー深部体温の連続計測と解析. 生体医工学 48 (3):269-280. doi:10.11239/jsmbe.48.269
血圧の計測技術開発
Development of a novel technique for measuring blood pressure
概要_Abstract
生理指標として最も重要な指標の一つである血圧の新しい計測技術を研究開発しています(^_^)
We are challenging to develop a novel technique for measuring blood pressure as one of significant physiological indeices.
発表論文_Articles
Matsumura K, Yamakoshi T, Rolfe P, Yamakoshi K (2017) Advanced volume-compensation method for indirect finger arterial pressure determination: comparison with brachial sphygmomanometry. IEEE Trans Biomed Eng 64 (5):1131-1137. doi:10.1109/TBME.2016.2591324
Tanaka S, Nogawa M, Yamakoshi T, Yamakoshi K (2007) Accuracy assessment of a noninvasive device for monitoring beat-by-beat blood pressure in the radial artery using the volume-compensation method. IEEE Trans Biomed Eng 54 (10):1892-1895. doi:10.1109/TBME.2007.894833
Yamakoshi K (2004) Non-invasive cardiovascular haemodynamic measurements. In: Oberg PA, Togawa T, Spelman F (eds) Sensors in Medicine and Health Care (Sensors Applications, Volume 3). Wiley-VCH Verlag, Weinheim, pp 107-160.
Yamakoshi K, Shimazu H, Togawa T (1980) Indirect measurement of instantaneous arterial blood pressure in the human finger by the vascular unloading technique. IEEE Trans Biomed Eng 27 (3):150-155. doi:10.1109/TBME.1980.326616
カフレス血圧推定技術とストレスの可視化・数値化技術開発
Development of a novel technique for cuffless blood pressure estimation and visualization of human stress
概要_Abstract
生理指標として最も重要な指標の一つである血圧をカフを用いず推定し、さらに身近なストレスを評価（可視化・数値化）できる新しい技術を研究開発しています(^_^)
We are challenging to develop a novel technique for estimating blood pressure as a one of significant physiological index, and for evaluating human stress.
発表論文_Articles
Yamakoshi T, Rolfe P, Yamakoshi K (2021) Cuffless blood pressure estimation based on haemodynamic principles: progress towards mobile healthcare. PeerJ 9:e11479. doi:10.7717/peerj.11479
Matsumura K, Rolfe P, Toda S, Yamakoshi T (2018) Cuffless blood pressure estimation using only a smartphone. Sci Rep 8 (1):7298. doi:10.1038/s41598-018-25681-5
松村健太, 李知炯, 山越健弘 (2016) スマートフォン式光電容積脈波測定法ー日常生活中における有効利用へ向けてー. 生体医工学 54 (3):120-128. doi:10.11239/jsmbe.54.120
山越健弘 (2009) 生理量の物理計測. In: 山口昌樹 (ed) ヒューマンインタフェースのための計測と制御. シーエムシー出版, 東京, pp 56-69.
山越健弘, 野川雅道, 山越憲一 (2008) ストレスの物理的評価. BIO INDUSTRY, vol 25. 東京, pp7-17.
多波長光電脈波を利用した血液成分計測技術開発
Development of a novel blood constituents measurement with multi-wavelength photoplethysmography
概要_Abstract
糖尿病患者支援・予防、安全運転支援のための多波長光電脈波を利用した採血不要の各種血液成分計測技術の研究開発をしています(^_^)
We are challenging to develop a novel technique for blood constituents measurement, named "pulse hemometry", for supporting diabetic patients and preventing drunk driving.
発表論文_Articles
Yamakoshi Y, Matsumura K, Yamakoshi T, Lee J, Rolfe P, Kato Y, Shimizu K, Yamakoshi KI (2017) Side-scattered finger-photoplethysmography: experimental investigations toward practical noninvasive measurement of blood glucose. J Biomed Opt 22 (6):67001. doi:10.1117/1.JBO.22.6.067001
Yamakoshi T (2017) Measuring blood alcohol concentration using only a smartphone. Impact 2019 (7):67-69. doi:10.21820/23987073.2019.7.67
Yamakoshi T, Lee J, Matsumura K, Yamakoshi Y, Rolfe P, Kiyohara D, Yamakoshi K (2015) Integrating sphere finger-photoplethysmography: preliminary investigation towards practical non-invasive measurement of blood constituents. PloS One 10 (12):e0143506. doi:10.1371/journal.pone.0143506
Ogawa M, Yamakoshi T, Motoi K, Nishida K, Yamakoshi Y, Yamakoshi K (2012) Determination of concentrations of glucose and human serum albumin in mixtures in phosphate-buffered solution by near-infrared spectroscopy. Sens Mater 24 (6):323-333.
Yamakoshi K, Yamakoshi Y (2006) Pulse glucometry: A new approach for noninvasive blood glucose measurement using instantaneous differential near-infrared spectrophotometry. J Biomed Opt 11 (5):054028-054021-054029. doi:10.1117/1.2360919
在宅ヘルスケアモニタリング技術開発
Development of a novel technique for healthcare monitoring using home furnishings
概要_Abstract
ヘルスケアに対する国民意識の高まりを背景に，健康モニタリング装置は小型・高利便性に向けて進歩しています。それに対応できるベッドやトイレなどの調度品を利用した新しい在宅用計測技術を研究開発しています(^_^)
We are challenging to develop a novel and advanced technique for helthcare monitoring using home furnishings.
発表論文_Articles
山越憲一 (2023) ヘルスケアモニタリング技術：最近の動向と今後の展開に向けて. BIO INDUSTRY, vol 40, no 9. 東京, pp11-25.
Yamakoshi K (2023) Healcare monitoring technology: resent advancements and toward progressive developments. BIO INDUSTRY, vol 40, no 9. Tokyo, pp11-25. https://schoo.jp/biz/column/1414
本井幸介, 菅沼美季, 山越康弘, 坂井宏旭, 山越憲一 (2021) 医療・介護における健康管理支援のためのベッドシーツ内蔵型体温計測システムの基礎的検討. 生体医工学 58 (6):219-229. doi:10.11239/jsmbe.58.219
Motoi K, Yamakoshi Y, Yamakoshi T, Sakai H, Tanaka N, Yamakoshi KI (2017) Measurement of electrocardiograms in a bath through tap water utilizing capacitive coupling electrodes placed outside the bathtub wall. Biomed Eng Online 16 (1):12. doi:10.1186/s12938-016-0304-9
山越憲一 (2017) 第6章第1節：住まいに溶け込む生体情報計測が果たす役割とヘルスケア・スマートタウンへの展開. In: 生体データ活用の最前線：スマートセンシングによる生体情報計測とその応用. サイエンス＆テクノロジー, 東京.
山越憲一 (2017) 第2章第9節：ウエアラブル身体活動・姿勢モニタリングと理学療法支援への応用. In: 生体データ活用の最前線：スマートセンシングによる生体情報計測とその応用. サイエンス＆テクノロジー, 東京.
Yamakoshi K (2011) Current status of noninvasive bioinstrumentation for healthcare. Sens Mater 23 (1):1-20
田中志信, 本井幸介, 野川雅道, 山越健弘, 山越憲一 (2006) ホームヘルスケアのための便座内蔵型血圧計測システムの試作. 生体医工学 44 (3):467-474. doi:10.11239/jsmbe.44.467
カームヘルスケアスマートタウン構想
Proposal of healthcare smart town based on calm monitoring with IoT technology
概要_Abstract
生活に溶け込むような新しいヘルスケア計測技術を研究開発しています(^_^)
We are challenging to develop a novel helthcare smart town based on calm monitoring with IoT technology.
実績_Achievements
山越憲一 (2023) ヘルスケアモニタリング技術：最近の動向と今後の展開に向けて. BIO INDUSTRY, vol 40, no 9. 東京, pp11-25.
Yamakoshi K (2023) Healcare monitoring technology: resent advancements and toward progressive developments. BIO INDUSTRY, vol 40, no 9. Tokyo, pp11-25. https://schoo.jp/biz/column/1414